157. Therapiekonzept bei der akuten Bein-Beckenvenenthrombose

Die Rolle der Gefäßwand in der Pathophysiologie des akuten Koronarsyndroms

Zusammenfassung Das Endothel ist in der Entstehung des akuten Koronarsyndroms von entscheidender Bedeutung. Als endo-/parakrines Organ nimmt das Endothel eine Schlüsselfunktion in der Regulation der vaskulären Homöostase ein. Die endotheliale Integrität und vor allem die Bioverfügbarkeit von Stickstoffmonoxid (NO) sind essenziell für die korrekte Funktion des Endothels. Kardiale Risikofaktoren ...

Die Rolle der Mastzellen bei der Atherosklerose

Rupture of an atherosclerotic plaque is the major underlying cause of adverse cardiovascular events such as myocardial infarction or stroke. Therapeutic interventions should therefore be directed towards inhibiting growth of atherosclerotic lesions as well as towards prevention of lesion destabilization. Interestingly, the presence of mast cells has been demonstrated in both murine and human pl...

Thrombozytenfunktionshemmer in der akuten und langfristigen Schlaganfallprävention

In primary prevention, aspirin reduces the risk of stroke but not of myocardial infarction in women while in men only the risk of myocardial infarction but not stroke could be significantly reduced. Only aspirin has been shown to be safe and effective in large randomized trials in the first 48 hours after ischemic stroke. Aspirin/dipyridamole and clopidogrel both reduce the risk of a combined c...

Optimale Blockauswahl bei der Kraftwerkseinsatzplanung

The paper addresses the unit commitment problem in power plant operation planning. For a real power system comprising coal and gas red thermal as well as pumped storage hydro plants a large-scale mixed integer optimization model for unit commitment is developed. Then primal and dual approaches to solving the optimization problem are presented and results of test runs are reported.

Individuelle Risikohandhabung bei der Zahlungssystemwahl